Drug Design - Cutting Edge Approaches |
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Edited by: Flower, Darren R. © 2002
Royal Society of Chemistry
Description: This book will be invaluable to all drug discovery scientists, including medicinal and combinatorial chemists, molecular modellers, bio- and cheminformaticians, and pharmacologists.
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Front Matter
Text
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Preface
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Table of Contents
1. Molecular Informatics: Sharpening Drug Design′s Cutting Edge
2. High-throughput X-Ray Crystallography for Drug Discovery
3. Trawling the Genome for G Protein-coupled Receptors: the Importance of Integrating Bioinformatic Approaches
4. Virtual Screening of Virtual Libraries - an Efficient Strategy for Lead Generation
5. Virtual Techniques for Lead Optimisation
6. The Impact of Physical Organic Chemistry on the Control of Drug-like Properties
7. Mutagenesis and Modelling Highlight the Critical Nature of the TM2-loop-TM3 Region of Biogenic Amine GPCRs
8. Computational Vaccine Design
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Index
